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Cephalon, Inc.; Zeneus Holdings Limited

Cephalon, Inc. Announces Agreement to Acquire Zeneus Holdings Limited

Frazer, Pennsylvania. and Oxford, England (ots/PRNewswire)

- Transaction Opens European Oncology Market for Cephalon; Creates
Additional Direct Presence in Europe's Five Major Markets
Cephalon, Inc. (Nasdaq: CEPH) and Zeneus Holdings Limited
announced today that the companies have signed a definitive purchase
agreement under which Cephalon, Inc. will acquire all of the
outstanding share capital of Zeneus Holdings for approximately US$360
million in cash. Zeneus Holdings is the parent company of Zeneus
Pharma Limited. The transaction is expected to close no later than
early in the first quarter of 2006. Cephalon expects the transaction
to generate approximately US$100 million in additional sales next
year and to be neutral to earnings in 2006 and accretive to earnings
thereafter.
The transaction will accelerate Cephalon's entry into the European
oncology market with several commercialized products, including
Myocet(R) (liposomal doxorubicin), a cardio-protective chemotherapy
agent used to treat late-stage breast cancer; Targretin(R)
(bexarotene), a treatment for cutaneous T-cell lymphoma; and
Abelcet(R) (amphotericin B lipid complex), an anti-fungal treatment.
Zeneus has 12 other marketed products as well as several
investigational compounds in early- or late-stage development.
With this acquisition, Cephalon will add offices in Spain and
Italy and bolster its existing presence in France, Germany and the
United Kingdom - which represent Europe's five largest pharmaceutical
markets. This transaction will add approximately 245 Zeneus Pharma
employees to Cephalon Europe, including 170 sales and marketing
professionals working across 18 countries. Cephalon also will add
offices in countries in Benelux, Scandinavia, and Northern, Central
and Eastern Europe when the transaction closes.
Zeneus Holdings is a privately held company backed by funds
advised by Apax Partners, a leading private equity investment group.
Zeneus Holdings will operate as a wholly owned subsidiary of
Cephalon, Inc.
"This agreement will significantly expand our product portfolio in
Europe and is consistent with our strategy and recent transactions in
the United States that create a platform from which we will grow our
oncology business," said Frank Baldino, Jr., Ph.D., Chairman and CEO
of Cephalon. "Zeneus Pharma is an excellent strategic fit for our
company."
Alain Aragues, President of Cephalon Europe, said, "Zeneus will
establish a broader, direct commercial presence for Cephalon in all
five major European markets. In addition to the products, we will add
pan-European capabilities in product registration, clinical research
and development, sales and marketing. This transaction also provides
access to the Spanish and Italian markets and the broad geographic
infrastructure necessary to continue growing our European business."
Steven Harris, CEO of Zeneus Pharma, said, "This transaction
highlights the quality of the Zeneus product portfolio and the
strength of its European marketing infrastructure. Since formation of
Zeneus in early 2004, we have created significant value in the
business. This combination with Cephalon is compelling and will
create a major pharmaceutical force in Europe."
N M Rothschild & Sons Limited acted as financial advisor to
Cephalon in this transaction.
Cephalon, Inc.
Founded in 1987, Cephalon, Inc. is an international
biopharmaceutical company dedicated to the discovery, development and
marketing of innovative products to treat sleep and neurological
disorders, cancer and pain. Cephalon currently employs approximately
2,500 people in the United States and Europe. U.S. sites include the
company's headquarters in Frazer, Pennsylvania, and offices,
laboratories or manufacturing facilities in West Chester,
Pennsylvania, Salt Lake City, Utah, and suburban Minneapolis,
Minnesota.
The company currently markets four proprietary products in the
United States: PROVIGIL(R) (modafinil) [C-IV], GABITRIL(R) (tiagabine
hydrochloride), ACTIQ(R) (oral transmucosal fentanyl citrate) [C-II]
and TRISENOX(R) (arsenic trioxide) injection, and more than 20
products internationally. Full prescribing information for all U.S.
products is available at http://www.cephalon.com or by calling
+1-800-896-5855.
Cephalon Europe
Cephalon Europe currently employs approximately 615 people. It
markets more than 20 pharmaceutical products such as ACTIQ(R) for
cancer pain; GABITRIL(R) for seizures associated with epilepsy;
modafinil under the brand names PROVIGIL(R), MODIODAL(R) and VIGIL(R)
for excessive sleepiness associated with multiple disorders;
SPASFON(R), an antispasmodic; and OTRASEL(R)/ZELAPAR(R) for
Parkinson's disease. Cephalon's European headquarters are located in
Maisons-Alfort, France. Other European sites include manufacturing
plants in Mitry-Mory and Nevers, France, and offices in
Maisons-Alfort, Guildford, England, and Martinsried, Germany.
Zeneus Pharma Limited
Zeneus Pharma is a European biopharmaceutical company with
substantial clinical, regulatory, sales and marketing operations in
Europe with worldwide sales through partner agreements. Zeneus Pharma
has a broad portfolio of specialist-marketed products currently
focused on oncology and critical care.
The company's European sales force, which has a direct presence in
16 countries and an indirect presence in others, sells to specialist
doctors in hospitals and other healthcare centers. Zeneus Pharma's
sales and marketing force, together with the company's other core
competencies in clinical development and regulatory affairs, provide
a window on Europe for U.S. and other pharmaceutical and
biotechnology companies that require a strong European partner.
Zeneus Pharma is a privately held European biopharmaceutical
company backed by funds advised by Apax Partners.
In addition to historical facts or statements of current
condition, this press release may contain forward-looking statements.
Forward-looking statements provide Cephalon's current expectations or
forecasts of future events. These may include statements regarding
the acquisition of Zeneus Holdings Limited, including the timing of
the expected closing of the transaction and the potential impact the
acquisition, if consummated, may have on 2006 sales and earnings,
Cephalon's entry into the European oncology market, its pan-European
capabilities and, more generally, the future growth of Cephalon's
European business; anticipated scientific progress on its research
programs; development of potential pharmaceutical products;
interpretation of clinical results; prospects for regulatory
approval; manufacturing development and capabilities; market
prospects for its products; sales and earnings guidance; and other
statements regarding matters that are not historical facts. You may
identify some of these forward-looking statements by the use of words
in the statements such as "anticipate," "estimate," "expect,"
"project," "intend," "plan," "believe" or other words and terms of
similar meaning. Cephalon's performance and financial results could
differ materially from those reflected in these forward-looking
statements due to general financial, economic, regulatory and
political conditions affecting the biotechnology and pharmaceutical
industries as well as more specific risks and uncertainties facing
Cephalon such as those set forth in its reports on Form 8-K, 10-Q and
10-K filed with the U.S. Securities and Exchange Commission. Given
these risks and uncertainties, any or all of these forward-looking
statements may prove to be incorrect. Therefore, you should not rely
on any such factors or forward-looking statements. Furthermore,
Cephalon does not intend to update publicly any forward-looking
statement, except as required by law. The Private Securities
Litigation Reform Act of 1995 permits this discussion.
Web site: http://www.cephalon.com

Contact:

Media, Robert Grupp, +1-610-738-6402, or rgrupp@cephalon.com, or
Investors, Chip Merritt, +1-610-738-6376, or cmerritt@cephalon.com,
both of Cephalon; or Marie-Dominique de la Salle of Cephalon Europe,
+33-(1)-49-81-82-48, or mddelasalle@cephalon.fr; or Steven Harris of
Zeneus Pharma, +44-(0)-1865-784821. Company News On-Call:
http://www.prnewswire.com/comp/134563.html