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Grünenthal GmbH

Grunenthal signs trimegestone licensing agreement for oral contraception

Aachen (ots)

The German pharmaceutical company Grunenthal
announces its worldwide exclusive rights on trimegestone for the use 
in oral contraception by Aventis Pharma, SA, France, a subsidiary of 
sanofi-aventis. Thereby the firm extends its gynaecological pipeline.
Trimegestone will be developed as a new oral contraceptive component 
derived from natural progesterone.
The agreement grants Grunenthal exclusive access to mainly 
preclinical data on trimegestone for the development of an oral 
contraceptive. Moreover it secures a mutually exclusive supply 
agreement: While Aventis Pharma, SA, holds the patent on the 
manufacturing synthesis process and provides for the production of 
the active ingredient trimegestone, Grunenthal will take care for the
formulation, the clinical development, registration, and marketing.
"With the development of a trimegestone containing oral 
contraceptive Grunenthal shows its strong commitment to become a 
major player in the field of gynaecology in the mid term", says Prof.
Dr. Eric-Paul Pâques, member of the Executive Board of Grunenthal."
About Trimegestone Trimegestone is a metabolically neutral & 
naturally derived progesterone agonist, thus long term acceptance for
female users is expected. Due to its favorable metabolic safety 
profile trimegestone is already in use in hormone replacement 
therapy. In this respect trimegestone is an ideal progestogen to be 
used in hormonal contraception.
About Grunenthal Grunenthal is an expert in pain therapy and 
gynaecology and a pioneer in intelligent, user-friendly drug delivery
technologies. Founded in 1946, the company employs 1,900 people in 
Germany and 4,800 worldwide. In 2006, Grunenthal achieved revenues of
813 million Euro.
Contact:

Contact:

Anke Krueger-Hellwig
Phone: +49 241 569-2858,
Fax: +49 241 569-1486,
anke.krueger-hellwig@grunenthal.com
Grunenthal GmbH,
52099 Aachen, Germany,
www.grunenthal.com

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