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Siemens Medical Solutions Diagnostics

Siemens Medical Solutions Diagnostics Inks Agreement with KreLo Medical Diagnostics to Expand Thyroid Immunoassay Menu

Deerfield, Illinois (ots/PRNewswire)

- Third-Generation TRAb Assay Delivers Unprecedented Specificity
for Diagnosing Graves' Disease
Siemens Medical Solutions Diagnostics
(www.siemens.com/diagnostics) announced that it has signed an
agreement with KreLo GmbH Medical Diagnostics for the rights to
develop an automated stimulating TSH receptor antibody (TRAb) assay
used in the differential diagnosis of Graves' disease. This agreement
will make Siemens Medical Solutions Diagnostics the first in vitro
diagnostics distributor of an automated TRAb assay featuring
stimulating TRAb KreLo antibodies which are specific to the diagnosis
of Graves' disease.
(Logo: http://www.newscom.com/cgi-bin/prnh/20070904/SIEMENSLOGO )
"The new TRAb assay has enormous potential to help diagnose,
monitor and predict the course of Graves' disease," said Joe
Bernardo, senior vice president, Central Lab Testing, Siemens Medical
Solutions Diagnostics. "Siemens continues to focus on new biomarker
development opportunities, continually expanding our already
comprehensive immunoassay menu and providing the diagnostic tools
necessary to diagnose and treat millions of thyroid disease
patients."
Graves' disease affects approximately 32 million people worldwide.
As one of the most common form of hyperthyroidism, Graves' is an
autoimmune disorder characterized by the presence of stimulating TSH
receptor autoantibodies found approximately 90 percent of Graves'
patients. TSH receptor autoantibodies mimic the activity of TSH,
leading to an elevated production of thyroid hormone. Left untreated,
Graves' disease can lead to miscarriage, birth defects, thyroid eye
disease and can be life-threatening.
Studies have shown that the TRAb test has the highest diagnostic
power to differentiate Graves' disease from toxic nodular goiters.
KreLo GmbH focuses on research and development of diagnostic kits for
application in human medicine. It was co-founded by Werner Kress and
Prof. Ulrich Loos, formerly professor at the Department of Medicine
at Ulm University (Ulm, Germany). Prof. Loos is the CEO of KreLo
GmbH.
About Siemens Medical Solutions Diagnostics
Siemens Medical Solutions Diagnostics is the leading clinical
diagnostics provider in the world. The company offers health care
professionals the broadest range of diagnostic products and services
that are used for diagnosing medical conditions, monitoring patient
therapy and providing quality health care. Siemens' comprehensive
portfolio of solutions and highly responsive service are designed to
improve clinical outcomes, streamline workflow and enhance the
operational efficiency of clinical laboratories around the world.
Visit www.siemens.com/diagnostics.
About Siemens Medical Solutions
Siemens Medical Solutions is one of the world's largest suppliers
to the healthcare industry. The company is a renowned medical
solutions provider with core competence and innovative strength in
diagnostic and therapeutic technologies as well as in knowledge
engineering, including information technology and system integration.
With its laboratory diagnostics acquisitions, Siemens Medical
Solutions will be the first fully integrated diagnostics company,
bringing together imaging and lab diagnostics, therapy, and
healthcare information technology solutions, supplemented by
consulting and support services. The company delivers solutions
across the entire continuum of care -- from prevention and early
detection, to diagnosis, therapy and care. Siemens Medical Solutions
employs more than 49,000 people worldwide and operates in 130
countries. According to IFRS, in the fiscal year 2007 (Sept. 30),
Siemens Medical Solutions reported sales of  euro 9.85 billion,
orders of euro 10.27 billion, and group profit of  euro 1.32 billion
(preliminary figures, unaudited). Further information can  be found
by visiting http://www.siemens.com/medical.
Web site: http://www.usa.siemens.com/medical
              http://www.siemens.com/diagnostics

Contact:

Amanda Naiman of Siemens Medical Solutions Diagnostics,
+1-610-448-4531, amanda.naiman@siemens.com / Photo: NewsCom:
http://www.newscom.com/cgi-bin/prnh/20070904/SIEMENSLOGO , AP
Archive: http://photoarchive.ap.org , PRN Photo Desk,
photodesk@prnewswire.com

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