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Epigenomics AG

EANS-News: Epigenomics AG Receives Allowance for Key Technology Patent in Japan

Patent broadly covers HeavyMethyl, a core technology of Epigenomics’ 
molecular diagnostic products
  Corporate news transmitted by euro adhoc. The issuer/originator is solely
  responsible for the content of this announcement.
Patents, Copyright & Trademarks/Molecular diagnostics
Subtitle: Patent broadly covers HeavyMethyl, a core technology of 
Epigenomics’ molecular diagnostic products
Press release, Berlin, Germany, and Seattle, WA, USA, March 11, 2010 
(euro adhoc) - Epigenomics AG (Frankfurt Prime Standard: ECX), a 
cancer molecular diagnostics company, today announced that it 
received a Notice of Allowance by the Japanese Patent Office stating 
that they intend to grant a patent for Epigenomics´ HeavyMethyl 
technology. This notification is equivalent to a "Rule 71(3) 
notification" by the European Patent Office. Patent application 
2002-571930 titled "Highly sensitive method for the detection of 
cytosine methylation patterns.", claims very broadly a method for the
detection of DNA methylation by means of amplification that employs 
blockers to prevent the amplification of background DNA while not 
affecting the amplification of target DNA. The patent is already 
granted in the US, Europe, China, Russia, Australia, South Korea, and
New Zealand.
The HeavyMethyl technology allows the specific and highly sensitive 
detection of methylated DNA in large background of unmethylated DNA 
using real-time PCR, the current industry technology standard in 
molecular diagnostics. The technology is currently used in 
Epigenomics´ own in vitro diagnostic products for the early detection
and diagnosis of cancer as well as in products of Epigenomics´ 
biomarker and technology licensees.
About Epigenomics
Epigenomics is a molecular diagnostics company with a focus on the 
development of novel products for cancer. Using DNA methylation 
biomarkers, Epigenomics´ tests on the market and in development aim 
at diagnosing cancer at an early stage before symptoms occur and 
thereby may reduce mortality from this dreaded disease.
Epigenomics´ product portfolio contains the CE-marked IVD test Epi 
proColon, the world´s first regulatory cleared molecular diagnostic 
test for the detection of colorectal cancer in blood that is based on
the biomarker Septin9, and further proprietary DNA methylation 
biomarkers and IVD products at various stages of development for 
colorectal, lung and prostate cancer. For development and global 
commercialization of IVD test products, Epigenomics pursues a dual 
business strategy in which direct commercialization of proprietary 
diagnostic test products is combined with non-exclusive licensing to 
diagnostic industry players with broad customer access. Strategic 
diagnostics industry partners include Abbott Molecular, Sysmex 
Corporation, Quest Diagnostics Incorporated, and ARUP Laboratories, 
Inc. for diagnostics test products and services, and QIAGEN N.V. for 
sample preparation solutions and research products. The company is 
headquartered in Berlin, Germany, and has a wholly owned subsidiary, 
Epigenomics Inc., in Seattle, WA, U.S.A. For more information, please
visit Epigenomics´ website at www.epigenomics.com.
Epigenomics legal disclaimers. This communication expressly or 
implicitly contains certain forward-looking statements concerning 
Epigenomics AG and its business. Such statements involve certain 
known and unknown risks, uncertainties and other factors which could 
cause the actual results, financial condition, performance or 
achievements of Epigenomics AG to be materially different from any 
future results, performance or achievements expressed or implied by 
such forward-looking statements. Epigenomics AG is providing this 
communication as of this date and does not undertake to update any 
forward- looking statements contained herein as a result of new 
information, future events or otherwise.
The information contained in this communication does not constitute 
nor imply an offer to sell or transfer any product, and no product 
based on this technology is currently available for sale in the 
United States. The analytical and clinical performance 
characteristics of any product based on this technology which may be 
sold at some future time in the U.S. have not been established.
end of announcement                               euro adhoc

Further inquiry note:

Epigenomics AG
Dr. Achim Plum
Sen. VP Corporate Development
Tel: +49 30 24345 368
achim.plum@epigenomics.com

Branche: Biotechnology
ISIN: DE000A0BVT96
WKN: A0BVT9
Index: Prime All Share, Technology All Share
Börsen: Frankfurt / regulated dealing/prime standard
Berlin / free trade
Hamburg / free trade
Stuttgart / free trade
Düsseldorf / free trade
München / free trade

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