Edmonton, Canada (ots/PRNewswire) - Isotechnika Inc. today announces the successful results of the Phase 2b PROMISE trial which were presented by Dr. A. Osama Gaber, an investigator for the PROMISE trial, at the 2008 American Transplant Congress in Toronto, Canada. The presentation detailed the final data ...
Edmonton, Canada (ots/PRNewswire) - Isotechnika Inc. will hold a conference call to discuss final Phase 2b PROMISE kidney transplant data for the Company's lead immunosuppressive drug, voclosporin, on Wednesday, June 4th at 9:00 a.m. ET/7:00 a.m. MT. As previously announced, the final Phase 2b kidney transplant trial (PROMISE) results will be presented during an ...
Edmonton, Canada (ots/PRNewswire) - Isotechnika Inc. announced today that voclosporin is positioned to enter a Phase 1 clinical trial as the drug utilized in the CINATRA(TM) Drug Coated Coronary Stent system developed by the Company's partner, Atrium Medical Corporation. Atrium has received approval from the ...
Edmonton, Canada (ots/PRNewswire) - Isotechnika Inc. (TSX:ISA) today announced positive results from the Phase 2b PROMISE trial which evaluated the Company's lead drug, voclosporin , in de novo kidney transplant patients. This trial was designed to determine the most appropriate dosing strategy for the Phase 3 program in kidney transplantation. "PROMISE has shown that the efficacy of voclosporin is statistically ...
Edmonton, Canada (ots/PRNewswire) - Isotechnika Inc. is pleased to announce that effective October 10, 2007, Mr. Clemens Kaiser will assume the role of Executive Vice President and Chief Marketing Officer. This position has been created to focus on pre-commercialization and commercialization efforts for the Company's lead drug, ISA247. Mr. Kaiser comes with extensive experience in the pharmaceutical industry as he ...
Edmonton, Canada (ots/PRNewswire) - Isotechnika today announced that the Company has received permission from the Food and Drug Administration of the United States (FDA) for the long term use of ISA247 in patients currently participating in the Company's Phase 2b kidney transplant (PROMISE) trial. The Company previously announced in June that it had also ...
Edmonton, Canada (ots/PRNewswire) - Isotechnika Inc. (TSX:ISA) announced today that the European Agency for the Evaluation of Medicinal Products (EMEA) committee for Orphan Medicinal Products has adopted a positive opinion on orphan medicinal product designation for ISA247 for the treatment of chronic, ...
Edmonton, Canada (ots/PRNewswire) - Isotechnika Inc. (TSX:ISA) announced today that the Company has completed recruitment of its pivotal Phase 3 European/Canadian psoriasis trial (ESSENCE). As of July 20, 2007, the Company closed recruitment at 638 patients. The patient population is made up of 228 Canadian patients, 294 patients from Germany and 116 patients from ...
Edmonton, Canada (ots/PRNewswire) - Isotechnika Inc. (TSX:ISA) announced today the enrolment of the last patient in its Phase 2b trial assessing ISA247 for the prevention of kidney graft rejection following transplantation. Of the 332 patients enrolled, 148 patients have already completed the required six months of treatment. The Company expects to have the last ...
Edmonton, Canada (ots/PRNewswire) - - Trades on Toronto Stock Exchange - (TSX:ISA) - www.isotechnika.com Isotechnika today announced that the Company has received a No Objection Letter from Health Canada for the long term use of ISA247 in patients currently participating in the Canadian arm of the Company's Phase 2b kidney transplant trial. The No ...
Edmonton, Canada (ots/PRNewswire) - - Trades on Toronto Stock Exchange - (TSX:ISA) Isotechnika Inc. announced today that the Company received approval from the Polish Competent Authority for participation in the ongoing Phase 3 European/Canadian clinical trial. This trial investigates the use of ISA247 ...
Edmonton, Alberta (ots/PRNewswire) - Isotechnika Inc. today announced the audited three month results, reviewed by the Data Monitoring Committee, of the first third of the patients treated in its Phase 2b de novo kidney transplant trial for the Company's lead immunosuppressive drug, ISA247. This interim analysis is based upon the assessment of the first 116 ...
Edmonton, Alberta (ots/PRNewswire) - Isotechnika Inc. will announce interim three month data from its Phase 2b kidney transplant trial for the Company's lead immunosuppressive drug, ISA247 on Monday, May 7th at 6:00 a.m. ET/4:00 a.m. MT. The management team will provide a review of the Phase 2b kidney transplant trial via a live conference call on Monday, May 7th ...
Edmonton, Canada (ots/PRNewswire) - - Trades on Toronto Stock Exchange - (TSX:ISA) Isotechnika today announced that the Company has been selected to give an oral presentation during the American Transplant Congress in San Francisco, California. An overview of the latest Phase 2b kidney transplant trial (PROMISE) results will be presented during an oral ...
Edmonton, Alberta (ots/PRNewswire) - Isotechnika will host an evening educational symposium at the American Transplant Congress. The evening symposium titled "Unleashing the Power of CNi's" will take place on Saturday, May 5th at 7:30 p.m. at the San Francisco Marriott Hotel. The symposium will highlight the use of ISA247 for the prevention of transplant ...
Edmonton (ots/PRNewswire) - - Company Set to Host Evening Symposium at ATC Isotechnika Inc. announced today that an independent data monitoring committee (DMC) has met and reviewed the interim data from the Phase 2b kidney transplant (PROMISE) trial. The review included 3 month data from approximately ...
Edmonton, Canada (ots/PRNewswire) - Isotechnika Inc. announced today that the Company has received approval from United States Adopted Name (USAN) for naming of its lead immunosuppressive drug, ISA247. The name, voclosporin, is now being reviewed by the International Nonproprietary Name (INN) expert committee. The INN is scheduled to publish the proposed list of ...
Edmonton, Canada (ots/PRNewswire) - Isotechnika Inc. (TSX: ISA) announced today that its partner, Lux Biosciences, has been granted orphan drug designation from the U.S. Food and Drug Administration (FDA) for ISA247, referred to as LX211 by Lux, for the treatment of non-infectious posterior, intermediate and ...
Edmonton, Canada (ots/PRNewswire) - Isotechnika Inc. (TSX: ISA) announced today that the Company has enrolled its first patient in a pivotal Phase III European/Canadian clinical trial for the treatment of moderate to severe psoriasis with its lead immunosuppressive drug, ISA247. The Phase III European/Canadian psoriasis trial (ESSENCE trial) will be performed at ...
Edmonton, Canada, November 28 (ots/PRNewswire) - Isotechnika Inc. (TSX:ISA) today announced that its lead immunosuppressive drug, ISA247 is positioned to enter Phase II/ III human clinical trials in uveitis by its partner Lux Biosciences, following interactions with the Food and Drug Administration and ...
Edmonton, Alberta, November 21 (ots/PRNewswire) - Isotechnika Inc. (TSX: ISA) today announced the Company has received a Notice of Allowance from the United States Patent and Trademark Office based on U.S. Patent Application Serial No. 10/845,747 for TAFA93, including both composition of matter and methods of use claims. This is the first patent to be issued in ...
Edmonton, Canada, November 16 (ots/PRNewswire) - - Transplant Data Presented at the American Society of Nephrology Conference Isotechnika Inc. today announced results from initial data for its Phase IIb kidney transplant trial of the Company's lead immunosuppressive drug, ISA247. To date, 133 patients have been enrolled in the trial. Based on an early ...
Edmonton, Canada, November 15 (ots/PRNewswire) - Isotechnika Inc. will announce initial data from its Phase IIb kidney transplant trial for the Company's lead immunosuppressive drug, ISA247 on Thursday, November 16th at 8:00 a.m. ET/6:00 a.m. MT. Dr. Randall Yatscoff, Isotechnika's President & CEO, will present the initial data via web cast commencing at 9:00 a.m. ...
Edmonton, Canada (ots/PRNewswire) - Isotechnika Inc. (TSX:ISA) reports final safety and efficacy data subsequent to 60 weeks of continuous treatment with ISA247. All safety and efficacy endpoints were met. Patients completing the 24 week Canadian Phase III SPIRIT trial were given the opportunity to continue ISA247 therapy at a 0.3 mg/kg twice daily oral dose ...
Edmonton, Canada (ots/PRNewswire) - Isotechnika Inc. announced today that the Company received a No Objection Letter from Health Canada to conduct a pivotal Phase III European /Canadian clinical trial for the treatment of moderate to severe psoriasis with its lead immunosuppressive drug, ISA247. The Company ...
Edmonton, Canada (ots/PRNewswire) - Isotechnika Inc. announced today that the Company has been issued European Patent No. EP0991660 for its lead immunosuppressive drug, ISA247. The patent entitled "DEUTERATED AND UNDEUTERATED CYCLOSPORINE ANALOGS AND THEIR USE AS IMMUNOMODULATING AGENTS" is the ninth patent to be issued internationally in this patent family. ...
Edmonton, Canada (ots/PRNewswire) - Isotechnika Inc. announced today that the Company received approval from the German Competent Authority to conduct a pivotal Phase III clinical trial for the treatment of moderate to severe psoriasis with its lead immunosuppressive drug, ISA247. The Phase III ...
Edmonton, Alberta (ots/PRNewswire) - - Isotechnika Inc. announced today promising results from its Phase I TAFA93 trials. TAFA93, a pro-drug of rapamycin, is a novel small molecule mTOR inhibitor, which is a class of drugs currently used in the prevention of organ rejection in transplantation. mTOR inhibitors are typically used in combination with ...
Edmonton, Canada (ots/PRNewswire) - Isotechnika Inc. announced today that the Company has signed an agreement with Lux Biosciences, Inc. of Jersey City, New Jersey granting Lux Biosciences worldwide rights to develop and commercialize Isotechnika's lead drug, ISA247 for the treatment and prophylaxis of all ophthalmic diseases. ISA247 is a novel calcineurin ...
Edmonton, Canada (ots/PRNewswire) - Isotechnika Inc. announced today that the Company has signed an option agreement with Cellgate Inc. of Redwood City, California. This agreement allows Isotechnika the option to obtain an exclusive license to develop and commercialize conjugates consisting of Cellgate's patented transporter technology for the topical delivery of ...