Calgary, Alberta (ots/PRNewswire) - Resverlogix Corp. ("Resverlogix" or the "Company") (TSX:RVX) is pleased to announce that key findings from the recently completed CANTOS trial, which demonstrate that targeting residual inflammatory risk resulted in a reduction in the incidence of Major Adverse Cardiovascular ...
Calgary, Alberta (ots/PRNewswire) - "BETonMACE Phase 3 Trial with apabetalone to expand to include the United States" Resverlogix Corp. ("Resverlogix" or the "Company") (TSX:RVX) is pleased to announce the receipt of a positive Type C written response from the Division of Metabolism and Endocrinology Products of the ...
Calgary, Alberta (ots/PRNewswire) - Resverlogix Corp. ("Resverlogix" or the "Company") (TSX:RVX) today announced that the first patient has been randomized in Taiwan in the Phase 3 BETonMACE clinical trial with lead drug apabetalone intended for high-risk patients with cardiovascular disease ("CVD") and type 2 ...
Calgary, Alberta (ots/PRNewswire) - The symposium titled: "Managing CKD, Diabetes & CVD: Is epigenetics a new way forward?" at the ERA-EDTA Congress highlights BET-inhibition and apabetalone in addressing the significant unmet medical need in chronic kidney disease and cardiovascular disease. Resverlogix Corp. ("Resverlogix" or the "Company") (TSX: RVX) today announced ...
Calgary, Alberta (ots/PRNewswire) - Apabetalone expands in to first orphan disease clinical trial in patients with Fabry disease Resverlogix Corp. ("Resverlogix" or the "Company") (TSX:RVX) today announced that it has received approval from Health Canada, Therapeutic Products Directorate, to proceed with a clinical ...
Calgary, Alberta (ots/PRNewswire) - Nature Reviews Nephrology and Pfizer Inc. discuss BET bromodomain inhibition and apabetalone as viable drug candidates Resverlogix Corp. ("Resverlogix" or the "Company") (TSX: RVX) today highlighted two additional works involving its lead drug, apabetalone, one recently published ...
Calgary, Alberta (ots/PRNewswire) - Apabetalone expands to a second major clinical indication in kidney dialysis patients Resverlogix Corp. ("Resverlogix" or the "Company") (TSX:RVX) is pleased to announce the acceptance, by the Cardiovascular and Renal Products Division of the U.S. Food and Drug Administration ...
Calgary, Alberta (ots/PRNewswire) - Several Key Proteins That Drive Kidney (Renal) Disease and Dialysis Risk are Downregulated After a Single Dose of Apabetalone Resverlogix Corp. ("Resverlogix" or the "Company") (TSX: RVX) today announced preliminary results from the New Zealand based Phase 1 trial with severe kidney (renal) impaired patients. The data showed ...
Calgary, Alberta (ots/PRNewswire) - The presentations at the ESC Congress symposium highlighted apabetalone and the opportunity and need for a novel approach to the treatment of high risk cardiovascular disease and diabetes. Resverlogix Corp. ("Resverlogix" or the "Company") (TSX:RVX) today announced that on Sunday, ...
Calgary, Alberta (ots/PRNewswire) - A data review by the independent Data Safety Monitoring Board resulted in a verbal recommendation for the BETonMACE trial to continue as planned without any modification. Resverlogix Corp. ("Resverlogix" or the "Company") (TSX:RVX) today announced that the independent Data and ...
Calgary, Alberta (ots/PRNewswire) - The commencement of this Phase 1 pharmacokinentic (PK) trial in patients with severe renal impairment is the first in a series of planned clinical trials designed with value creation in mind. Resverlogix Corp. ("Resverlogix" or the "Company") (TSX:RVX) today announced that dosing has commenced in a Phase 1 PK study with lead drug ...
Calgary, Alberta (ots/PRNewswire) - "Apabetalone, a selective bromodomain extra-terminal (BET) protein inhibitor that significantly decreases abundance and activity of complement proteins" Resverlogix Corp. ("Resverlogix" or the "Company") (TSX:RVX) announces that new data was presented at the ERA-EDTA Congress in ...
Calgary, Alberta (ots/PRNewswire) - Apabetalone will be evaluated in a Phase 3 clinical trial in high-risk coronary artery disease and type 2 diabetes mellitus patients Resverlogix Corp. (the "Corporation") today announced the commencement of a Phase 3 clinical trial called 'BETonMACE' with lead drug apabetalone (RVX-208) in high-risk patients with coronary artery ...
Calgary, Alberta (ots/PRNewswire) - - TSX Exchange Symbol: RVX Resverlogix Corp. ("Resverlogix") announced today that it has closed the previously-announced private placement with Shenzhen Hepalink Pharmaceutical Co., Ltd. ("Hepalink") and Eastern Capital Limited ("Eastern"). Under the terms of the transaction, Hepalink subscribed for 13,270,000 units, each unit ...
Calgary, Alberta (ots/PRNewswire) - TSX Exchange Symbol: RVX Resverlogix Corp. ("Resverlogix") announced today that it has closed a license agreement and formally entered into a definitive stock purchase agreement with Shenzhen Hepalink Pharmaceutical Co., Ltd. ("Hepalink"). The closing of the stock purchase ...
Calgary, Alberta (ots/PRNewswire) - TSX Exchange Symbol: RVX Resverlogix Corp. today announced that following recent meetings with various European regulatory bodies, the first confirmation for our Phase 3 clinical plan has officially been received. A further regulatory and protocol design update will be provided to the market post the approval of additional regulatory ...
Calgary, Alberta (ots/PRNewswire) - RVX-208, the first selective bromodomain extra-terminal (BET) protein inhibitor, significantly reduces alkaline phosphatase (ALP) levels in patients with high vascular risk Resverlogix Corp. (the "Company") today announced that new data on RVX-208 was presented at the ERA-EDTA ...
Calgary, Alberta (ots/PRNewswire) - The deal structure involves CAD$50 million in equity investments, and future China sales milestones and licensing royalties that could represent in excess of US$400 million Resverlogix Corp. ("Resverlogix" or the "Company") today announced that it has entered into a Framework ...
Calgary, Alberta (ots/PRNewswire) - Resverlogix Corp. ("Resverlogix" or the "Company") announces that it has received two China patent approvals covering RVX-208. A composition of matter patent, China No. 2007 8 0052349.8 titled, "Compounds for the Prevention and Treatment of Cardiovascular Disease" was granted until February 2027. A manufacturing patent, China No. ZL 2009 8 0106586.7 titled, "Methods of Preparing ...
Calgary, Alberta (ots/PRNewswire) - In addition, preliminary results from an Australian sponsored trial have yet to verify whether the mechanism of RVX-208 action may affect glucose metabolism. Resverlogix Corp. announced today findings from the recent analysis of Major Adverse Cardiovascular Events (MACE) data in ...
Calgary, Alberta (ots/PRNewswire) - "RVX-208 treated patients have significant lower MACE events in high risk CVD patients" TSX Exchange Symbol: RVX Resverlogix Corp. today announced new information arising from its ongoing analysis of data from both the SUSTAIN and ASSURE trials in atherosclerotic patients with high risk for recurrent events. This analysis, performed ...
Calgary, Alberta (ots/PRNewswire) - "In patients with low HDL receiving RVX-208 and Rosuvastatin (Crestor(R)), plaque regression was twice as pronounced as compared to the pre-specified primary endpoint." TSX Exchange Symbol: RVX Resverlogix Corp. today announced the Full Analysis Set (FAS) data from 281 treated ...
Calgary, Alberta (ots/PRNewswire) - TSX Exchange Symbol: RVX Resverlogix Corp. today announced they will be hosting a corporate update conference call and webcast with Q&A on September 3rd at 11 am MDT. Details for the conference call and webcast are as follows: Link to webcast: http://services.choruscall.ca/links/resverlogix130905.html Dial in numbers: Canada & USA Toll Free Dial In: 1-800-319-4610 Outside of Canada & ...
Calgary, Alberta (ots/PRNewswire) - IVUS data will evaluate plaque regression in patients with high-risk Cardiovascular Disease TSX Exchange Symbol: RVX Resverlogix Corp. today announced that it has completed dosing in ASSURE, a Phase 2b clinical trial evaluating RVX-208, Resverlogix's first-in-class orally active BET-protein inhibitor, using intra-vascular ultrasound (IVUS) in high-risk cardiovascular patients with low ...
Calgary, Canada (ots/PRNewswire) - Transaction Designed to Enhance Shareholder Value By Unlocking Value of the Epigenetics Platform TSX Exchange Symbol: RVX Resverlogix Corp. ("Resverlogix") today announced that its Board of Directors has approved a proposal to spin-out its subsidiary, RVX Therapeutics Inc. ("RVX Therapeutics"), which will focus on innovative drug research and development by leveraging its epigenetics ...
Calgary, Alberta (ots/PRNewswire) - IVUS data will evaluate plaque regression in patients with Coronary Artery Disease TSX Exchange Symbol: RVX Resverlogix Corp. today announced that it has completed enrollment in ASSURE, a Phase 2b clinical trial targeting high-risk cardiovascular disease patients. ASSURE will evaluate the ability of RVX-208, Resverlogix's BET protein inhibitor, to regress atherosclerotic disease versus ...
Munich And Calgary, Alberta (ots/PRNewswire) - -- Significant Increase in Functional HDL Persisted Throughout the 24-week Study Period -- -- Results from ASSURE Study Expected H1 2013, Using IVUS to Measure Regression of Atherosclerotic Plaque -- TSX Exchange Symbol: RVX Resverlogix Corp. today announced that the ...
Calgary, Alberta (ots/PRNewswire) - This Novel Epigenetic Mechanism Defines an Entirely New Class of Therapeutic TSX Exchange Symbol: RVX Resverlogix Corp. ("Resverlogix" or the "Company") today announces the "Mechanism of Action" (MoA) by which RVX-208 increases apolipoprotein A-I (ApoA-I) production. Our data shows RVX-208 to be an inhibitor of the Bromodomain and ...
Calgary, Alberta (ots/PRNewswire) - Dr. Stephen J. Nicholls joins as guest speaker TSX Exchange Symbol: RVX Resverlogix Corp. ("Resverlogix" or the "Company") is pleased to announce for the first time the "Mechanism of Action" (MoA) by which RVX-208 increases apolipoprotein A-I (ApoA-I) production. Please join us via Conference Call & Webcast on Monday, April 23, 2012, ...
Calgary (ots/PRNewswire) - Resverlogix Corp. ("Resverlogix") announced today that two abstracts on the analysis of the ASSERT trial were presented at the European Society of Cardiology (ESC) Congress 2011 in Paris, France. The abstracts were co-authored by Resverlogix Senior Scientists and Clinical Steering ...